Ch. 6: Advanced Genetics
Reading
BJU Biology: Ch. 6 -The modern understanding of heredity, including chromosomes and genes
AP Princeton Review: Ch. 9 Gene Expression and Regulation
Topics
Labs
BJU Biology: Ch. 6 -The modern understanding of heredity, including chromosomes and genes
AP Princeton Review: Ch. 9 Gene Expression and Regulation
Topics
- Mutations
- Gene expression and regulation
- Biotechnology
Labs
- "From DNA to Protein Structure & Function" (lab handout will be provided)
- Transgenic Fly weblab
Examples of genetic engineering (discuss)
- Gene therapy - Gilead Science's Car T-cell therapy (Kymriah & Yescarta) for Leukemia - review the cost!!
- Insulin production - from Banting & Best's original patent to Genentech and Ely Lilly making recombinant 'human' insulin
- DNA Fingerprinting - uses PCR, restriction enzymes, and gel electrophoresis
- Agriculture - Monsanto's Roundup Ready "RR" corn, and Bt corn & cotton
Video clips below: We will watch and discuss in class
Homework
Hosted in Canvas
Hosted in Canvas
Transgenic Fly weblab
www.biointeractive.org/classroom-resources/transgenic-fly-virtual-lab
2025 NOTE: HHMI has now turned this into a multi-hour lab project with 50 questions. Consider using it as a Capstone Project.
www.biointeractive.org/classroom-resources/transgenic-fly-virtual-lab
2025 NOTE: HHMI has now turned this into a multi-hour lab project with 50 questions. Consider using it as a Capstone Project.