Ch. 6: Advanced Genetics 

Reading
BJU Biology: Ch. 6 -The modern understanding of heredity, including chromosomes and genes
AP Princeton Review: Ch. 9 Gene Expression and Regulation​​​

Topics
  • Mutations
  • Gene expression and regulation
  • Biotechnology

Labs
  • "From DNA to Protein Structure & Function"  (lab handout will be provided) ​
  • ​Transgenic Fly weblab ​
​Examples of genetic engineering (discuss)
  • Gene therapy - Gilead Science's Car T-cell therapy (Kymriah & Yescarta) for Leukemia - review the cost!!
  • Insulin production - from Banting & Best's original patent to Genentech and Ely Lilly making recombinant 'human' insulin
  • DNA Fingerprinting - uses PCR, restriction enzymes, and gel electrophoresis
  • Agriculture - Monsanto's Roundup Ready "RR" corn, and Bt corn & cotton​
Video clips below: We will watch and discuss in class
Homework
Hosted in Canvas
Transgenic Fly weblab
www.biointeractive.org/classroom-resources/transgenic-fly-virtual-lab 
2025 NOTE: HHMI has now turned this into a multi-hour lab project with 50 questions. Consider using it as a Capstone Project.